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Ep 113: Obesity, The Real Pandemic – Cause, Effect and The Solution

As we fly through the universe of crazy these days, we are ignoring the biggest elephant (figuratively and literally) in the room, causing the most harm in this country: obesity. In America, it will not be a murky virus, economic ruin, or even terrorism that does us in–it appears it will be our inability to put down a fork and knife. Our waistlines are exploding, we are on numerous pharmaceutical drugs, yet we ignore the easiest solution to our weight gain woes: regular exercise and eating healthy. But what does that really mean?

We will dig into the numbers, and I will warn you they are not pretty. To say we are fat as a nation is putting it nicely. The facts tell a very disturbing problem in our society, and it is getting worse at an alarming rate.

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Today I bring on my favorite scientist and data analyst to help me go through the numbers–Madame X. Yes, she has to use an alias, well, because people are crazy. 

Topics Discussed:

* What the do the statistics really say about obesity

* What is the “Healthcare Industrial Complex”

* Why there is no money in healthy people

* Why being fat is not beautiful and definitely not healthy

* Why optimal health is the key to not getting Covid, not getting vaccinated 

* Is it possible some of us are genetically skewed to be overweight, or obese

* Can you beat bad genetics and still live a life of optimal health and wellness

* Why it is easy to maintain a healthy weight and lifestyle if you just pay attention

* Why health fads are fads for a reason

* Why your poor health negatively impacts everyone around you

Episode Resources:

* Link to Gary’s World Famous Health Book: https://www.thesimplelifenow.com/product/the-simple-life-guide-to-optimal-health-softcover/

* The Simple Life Website: https://www.thesimplelifenow.com 

*Make sure to signup and be a member of The Simple Life Insider’s Circle at: https://www.thesimplelifenow.com/the-simple-life/

Show Links:

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Qian at el J Med Econ 2015;18(12):1020___ Prevalence and healthcare costs of obesity related comorbidities: evidence form an electronic medical records system in the United States 

Ravelli GP, Stein ZA, Susser MW. Obesity in young men after famine exposure in utero and early infancy. N Engl J Med 1976; 295: 349–353.

Huang C, Li Z, Wang M, Martorell R. Early life exposure to the 1959-1961 Chinese famine has long-term health consequences. J Nutr 2010; 140: 1874–1878.

age’ > 85th percentile vs infants in WFA < 85th percentile

Parrillo L et al International Journal of Molecular Sciences 19 June 2019 Nutritional Factors, DNA Methylation and risk of Type2 diabetes and Obesity- Perspectives and Challenges

Newborns of obese parents have altered DNA methylation patterns at imprinted genes 

Soubry et al, International Journal of Obesity (2015) 39, 650-657

Insulin like growth factor (IGF2) and H19 methylation at birth and risk of overweight and obesity in children. 

Perkins, E. et al J Pediatrics Jul 16(1)31-39

Valleso,L,et,al_IntJObes(2011)Dec;35(12)_Altered Hypothalamic Function in Diet-Induced Obesity

Review of animal studies 

Alexander,J_JClinInvest(2017);127(1)24-32, Hypothalamic Inflammation in obesity and metabolic disease

remarkable how rapidly overconsumption of a fat-rich diet results in acute changes in the feedback to metabolic endocrine signals (such as leptin and insulin signaling) and in hypothalamic inflammatory responses

Obri et al_Cell Stress | JULY 2019 | Vol. 3 No. 7_Role of Epigenetics in hypothalamic energy balance control: implications for obesity

Thomas K., et al, NatureResearch (2019)9:17373

Fotuhi et al Practical Neurology July 2013

Kim J et al, International J of Obesity 44, 1197 (2020)

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